Mathematical Modeling of Invasive Carcinoma: Biomechanics of Small Groups of Cancer Cells

According to the latest research, cancer is a complex biological system that evolves over time and space. This means cells differ from each other in their functions tumor. They engage various interactions with microenvironment compete for available nutrients survive. The main problem of mathematical modeling oncology today heterogeneity typical malignant neoplasm. In this work, we propose chemomechanical model pattern formation small groups invasive carcinoma non-special type (IC NST). assumes heterogeneous formation, which consists different phenotypes performing tasks maintain existence model, cell represented as deformable polygon changes its shape size tissue develops. Numerical implements subtypes IC NST structures. These patterns are compared morphological structures identified clinical studies.